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PPARγ agonist 19

SKU: orb3135695

Description

PPARγ agonist19 (Compound 5e) is a PPARγ agonist with an IC50 of 11.27 μM for COX-1 and 0.05 μM for COX-2. It enhances glucose uptake in rat hemidiaphragm assays more effectively than pioglitazone. Additionally, PPARγ agonist19 reduces hyperglycemia and insulin resistance in type 2 diabetic rat models and protects against renal and lipid damage caused by metabolic dysfunction.

Research Area

Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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TargetCOX,PPAR

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information