Podofilox

SKU: orb1309699

Description

Podofilox, also known as (+)-Shikonin, is a lignan derived from Podophyllum resin. It acts as a potent spindle poison and keratolytic agent, making it a research tool for studying antimitotic mechanisms, wart treatments, and potential antineoplastic applications in both in vitro and in vivo models.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 518-28-5
• MW: 414.4053
• Purity: 99.73% (May vary between batches)
• Formula: C₂₂H₂₂O₈
• SMILES: COC1=CC(=CC(OC)=C1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)C2=C1C=C1OCOC1=C2
• Target: Topoisomerase,Microtubule Associated
• Solubility: DMSO:25 mg/mL (60.33 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.41 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(+)-Shikonin, inhibit, MicrotubuleAssociated, Microtubule/Tubulin, microtubule, Microtubule Associated, Inhibitor, Topo II, Podophyllotoxin, Podofilox, Shikonin

Compound Identifiers

PubChem CID

10607