Paclitaxel-2′-succinate NHS ester

SKU: orb3134779

Description

Paclitaxel-2′-succinate NHS ester is a derivative of paclitaxel featuring a succinate linker with its carboxyl group activated as an NHS ester. The NHS ester moiety exhibits high reactivity towards amino or hydroxyl groups, facilitating its conjugation with various molecules (such as peptides, proteins, antibodies, enzymes, or polymers). This compound is utilized in the development of nanomedicines and cancer research.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 245110-80-9
• MW: 1051.05
• Formula: C₅₅H₅₈N₂O₁₉
• SMILES: O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)OC(CCC(ON8C(=O)CCC8=O)=O)=O)=O)C5)[H]
• Target: Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Microtubule Associated