p-Hydroxybenzaldehyde

SKU: orb1222798

Description

4-Hydroxybenzaldehyde shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic acid, a known anticonvulsant.

Images & Validation

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Key Properties

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CAS Number	123-08-0
MW	122.12
Purity	>98% (HPLC)
Formula	C₇H₆O₂
SMILES	C1=CC(=CC=C1C=O)O
Target	GABA transaminase
Solubility	In Vitro: DMSO : 100 mg/mL (818.87 mM)

Bioactivity

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In Vitro	p-Hydroxybenzaldehyde (4-hydroxybenzaldehyde) is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde (101.7 μM) significantly reduces the GABA-induced chloride current of GABAA receptors expressed on Xenopus oocytes.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

GABA transaminase

Protocol Information

Find More Protocols

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