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OTS964

SKU: orb1688237

Description

OTS964 is a potent, orally bioavailable small molecule that selectively inhibits TOPK (IC₅₀ = 28 nM) and binds CDK11B with high affinity (Kd = 40 nM). It is a valuable research tool for investigating oncology pathways and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1338542-14-5
MW392.51
FormulaC23H24N2O2S
SMILESOC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C([C@H](CN(C)C)C)C=C4
TargetCDK,Others,TOPK,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information