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Ondansetron

SKU: orb1300614

Description

Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist primarily utilized to prevent nausea and vomiting. It is widely employed in both in vitro binding assays and in vivo studies to investigate emesis pathways, chemotherapy-induced nausea, and postoperative nausea.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number99614-02-5
MW293.363
Purity99.92% (May vary between batches)
FormulaC18H19N3O
SMILESCN1C2=C(C3=C1C=CC=C3)C(=O)C(CN1C=CN=C1C)CC2
Target5-HT Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.41 mM);DMSO:4 mg/mL (13.64 mM)

Bioactivity

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Target IC50
5-HT:103 pM

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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5-HT3, 5HT Receptor, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5-HT, 5HTReceptor, GR38032, GR-38032, GR 38032F, GR 38032, GR-C507/75, inhibit, Inhibitor, Ondansetron, SN307, SN-307, SN 307, Serotonin Receptor

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Quality Guarantee

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Key Properties

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No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
25 mg
$ 90.00
100 mg
$ 110.00
200 mg
$ 140.00
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