Octoclothepine

SKU: orb3210546

Description

Octoclothepine (Clorotepine), an analogue of Clozapine, is both a neuroleptic and antipsychotic agent. It exists in enantiomeric forms, where the (+) form acts as an atypical antipsychotic, and the (-) form functions as a typical antipsychotic. The (+)-Octoclothepine displays very high binding affinity for 5-HT₆ and 5-HT₇ receptors, with Ki values of 0.41 and 0.38 nM respectively, whereas the (-)-Octoclothepine shows Ki values of 17.7 and 1.3 nM. This compound is utilized in research related to schizophrenia.

Key Properties

• CAS Number: 13448-22-1
• MW: 344.90
• Formula: C₁₉H₂₁ClN₂S
• SMILES: ClC1=CC=C2SC=3C=CC=CC3CC(C2=C1)N4CCN(C)CC4
• Target: 5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

5-HT Receptor