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O-Desmethyl Midostaurin

SKU: orb1708995

Description

O-Desmethyl Midostaurin is the pharmacologically active metabolite of Midostaurin, formed via hepatic cytochrome P450 metabolism. This small molecule is a key research tool for investigating targeted FLT3 kinase inhibition in both in vitro biochemical assays and in vivo models of acute myeloid leukemia (AML).

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number740816-86-8
MW556.61
FormulaC34H28N4O4
SMILESC[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CNC6=O)C=8C(N5[C@](O1)(C[C@@H](N(C(=O)C9=CC=CC=C9)C)[C@H]2O)[H])=CC=CC8
TargetPKC,Others

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

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No computed properties available.

Protocol Information