NS11394

SKU: orb1306577

Description

NS11394 is a subtype-selective positive allosteric modulator of GABA(A) receptors, demonstrating a functional selectivity profile of α5 > α3 > α2 > α1. This compound is a valuable research tool for investigating the roles of specific GABA(A) receptor subtypes in neurological and psychiatric conditions, applicable in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 951650-22-9
• MW: 353.42
• Purity: 99.86% (May vary between batches)
• Formula: C₂₃H₁₉N₃O
• SMILES: CC(C)(O)c1ccc2n(cnc2c1)-c1cccc(c1)-c1ccccc1C#N
• Target: GABA Receptor
• Solubility: DMSO:60 mg/mL (169.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.66 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

pain, neuropathi, inhibit, Inhibitor, NS 11394, NS11394, NS-11394, inflammatory, electrophysiological, Gamma-aminobutyric acid Receptor, GABAA, GABA Receptor, GABAReceptor, Freund's, Anxiety, adjuvant, cord, Complete, γ-Aminobutyric acid Receptor, pinal

Compound Identifiers

PubChem CID

16747643