Neostigmine methyl sulfate

SKU: orb1308019

Description

Neostigmine methyl sulfate is a peripherally-acting, reversible acetylcholinesterase inhibitor used to treat myasthenia gravis. It is a research tool for studying cholinergic transmission in vitro and for modeling peripheral cholinergic enhancement in vivo, due to its inability to cross the blood-brain barrier.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 51-60-5
• MW: 334.39
• Purity: 99.90% (May vary between batches)
• Formula: C₁₃H₂₂N₂O₆S
• SMILES: c1(cc(ccc1)[N+](C)(C)C)OC(=O)N(C)C.S(=O)(=O)(OC)[O-]
• Target: Cholinesterase (ChE),AChR
• Solubility: DMSO:55 mg/mL (164.48 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.98 mM);H2O:200.4 mM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, Hodostin, inhibit, Normastigmin, Neostigmine methyl, Neostigmine methyl sulfate, Neostigmine methyl Sulfate, Cholinesterase (ChE), AChE, AChR, Syntostigmin

Compound Identifiers

PubChem CID

5824