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NDM-1-IN-10

SKU: orb3173322

Description

NDM-1-IN-10 (Compound CS-23) is an irreversible covalent inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) with an IC50 of 36 nM. It displays synergistic effects with Meropenem against E. coli expressing NDM-1, with a minimum inhibitory concentration (MIC) of 0.25 μg/mL for E. coli BL21/pET15b-blaNDM-1. NDM-1-IN-10 is applicable in bacterial infection research.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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CAS Number3044733-61-8
MW444.47
FormulaC18H13NaO6S3
SMILES[Na].O=C1C2=CC=C(SC=3SC=4C=CC=CC4C3)C=C2OC=C1C(O)S(=O)(=O)O
TargetAntibacterial

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information