Mycophenolic acid

SKU: orb1308937

Description

Mycophenolic acid

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 24280-93-1
• MW: 320.35
• Purity: >98%
• Formula: C₁₇H₂₀O₆
• SMILES: COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
• Target: Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)
• Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 30 mg/ml).

Bioactivity

• In Vivo:
  In cultured human, mouse, and rat T lymphocytes and B lymphocytes, Mycophenolic acid inhibits mitogen-induced proliferative responses. Mycophenolic acid can also induce apoptosis in activated CD4+ T cells.
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• In Vitro:
  In murine models, Mycophenolic acid selectively inhibits lymphocyte proliferation, cellular-mediated immune responses, and humoral immune responses.

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC129185

Compound Identifiers

PubChem CID

446541