MPEP HCl

SKU: orb1305394

Description

MPEP hydrochloride is a potent and selective non-competitive antagonist of the metabotropic glutamate receptor 5 (mGlu5), exhibiting an IC50 of 36 nM. It is a valuable research tool for investigating mGlu5 function in neurological and psychiatric disorders, widely used in both in vitro binding assays and in vivo behavioral studies.

Research Area

Neuroscience

Key Properties

• CAS Number: 219911-35-0
• MW: 229.71
• Purity: >98%
• Formula: C₁₄H₁₁N·HCl
• SMILES: Cl.Cc1cccc(n1)C#Cc1ccccc1
• Target: GPCR
• Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).

Bioactivity

• Target IC50:
  mGlu5:36 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, MPEP, MPEP hydrochloride, MPEP Hydrochloride, mGluR, Metabotropic glutamate receptors

Compound Identifiers

PubChem CID

9794588