ML-030

SKU: orb1220046

Description

ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively)

Key Properties

• CAS Number: 1013750-77-0
• MW: 412.46
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₀N₄O₄S
• SMILES: COc1ccc(OC)c(c1)-c1nnc2SCC(=Nn12)c1ccc(OC)c(OC)c1
• Target: PDE
• Solubility: DMSO:45 mg/mL (109.1 mM; Need ultrasonic)

Bioactivity

• In Vitro:
  ML-030 is potent in cell-based assay with an EC50 value of 18.7 nM.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE