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MG16

SKU: orb3211017

Description

MG16 is a prodrug of 10-Methoxycamptothecin. It functions by downregulating CDK6 and upregulating ASK1 expression. MG16 can induce cell cycle arrest and apoptosis (Apoptosis). Furthermore, it exhibits anticancer activity against Lewis lung carcinoma, small cell lung cancer, and non-small cell lung cancer.

Images & Validation

Key Properties

CAS Number2349329-01-5
MW471.89
FormulaC23H22ClN3O6
SMILESO(C(CN)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC=C(OC)C5)COC1=O.Cl
TargetCDK,Apoptosis,ASK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information