Metallo-β-lactamase-IN-6

SKU: orb1689764

Description

Metallo-β-lactamase-IN-6 is a potent small-molecule inhibitor of VIM-type metallo-β-lactamases, showing low micromolar IC₅₀ values against VIM-2, VIM-1, and VIM-5. It demonstrates strong synergistic antibacterial activity with meropenem in vitro against engineered E. coli and clinical P. aeruginosa strains harboring VIM-2, supporting research into overcoming carbapenem resistance.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1439899-44-1
• MW: 203.2
• Formula: C₁₀H₉N₃O₂
• SMILES: OC(=O)c1nccn1Cc1ccncc1
• Target: Antibacterial,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86276926