Mefloquine hydrochloride

SKU: orb1310226

Description

Mefloquine hydrochloride is a quinoline-based antimalarial agent effective against Plasmodium falciparum. It is widely used in malaria research for both chemoprevention and treatment studies, serving as a critical tool in parasitology for in vitro assays and in vivo animal models of infection.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 51773-92-3
• MW: 414.77
• Purity: 99.99% (May vary between batches)
• Formula: C₁₇H₁₇ClF₆N₂O
• SMILES: [C@@H](O)([C@@H]1NCCCC1)c1cc(nc2c1cccc2C(F)(F)F)C(F)(F)F.Cl
• Target: Potassium Channel,SARS-CoV,Reactive Oxygen Species,Parasite,Autophagy,ROS Kinase
• Solubility: DMSO:35.71 mg/mL (86.1 mM);Ethanol:76 mg/mL (183.23 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.82 mM)

Bioactivity

• Target IC50:
  K+ channel:1 microM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AMPK, anticancer, antimalarial, Autophagy, Inhibitor, Mefloquin, Mefloquin hydrochloride, Mefloquin Hydrochloride, Mefloquine, Mefloquine HCl, Mefloquine hydrochloride, Mefloquine Hydrochloride, ERK, KcsA, inhibit, JNK, Parasite, Reactive Oxygen Species, ReactiveOxygenSpecies, Potassium Channel, PotassiumChannel, ROS, SARSCoV, SARS coronavirus, SARS-CoV

Compound Identifiers

PubChem CID

65329