Liquidambaric lactone

SKU: orb1940923

Description

Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.Among the 25 fractions obtained from the alcohol extractive of the roots of Lantana camara L.(Verbenaceae) by silica gel column chromatography,three fractions demonstrated inhibitory HIV-1 reverse transcriptase activity.Furthermore,six pentacyclic triterpenes were isolated by reduced pressure column chromatography and identified as oleanonic acid(1),Liquidambaric lactone(2),lantadene A(3),lantadene B(4),oleanolic acid(5),and 25-hydroxy-oleanolic acid(6) by spectral analysis. Compounds 2 and 6 were reported firstly in the plants of Verbenaceae family,and the structure of 6 was confirmed firstly by X-ray crystallography.

Key Properties

• CAS Number: 185051-75-6
• MW: 468.67
• Purity: >98% (HPLC)
• Formula: C₃₀H₄₄O₄
• SMILES: C[C@]1([C@@]2(CC[C@@]3([H])C4(C)C)C)[C@@]([C@@H](O5)[C@@H]5[C@]2([H])[C@]3(CCC4=O)C)(OC6=O)[C@@](CC(C)(C)CC7)([H])[C@]67CC1
• Target: HIV

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

HIV