Ligupurpuroside A

SKU: orb1684458

Description

Ligupurpuroside A

Research Area

Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 147396-01-8
• MW: 770.73
• Purity: 99.80% (May vary between batches)
• Formula: C₃₅H₄₆O₁₉
• SMILES: CC1OC(OC2C(C)OC(OC3C(O)C(OCCc4ccc(O)c(O)c4)OC(CO)C3OC(=O)C=Cc3ccc(O)c(O)c3)C(O)C2O)C(O)C(O)C1O
• Target: Lipase,Lipid

Bioactivity

• In Vitro:
  The present study was carried out to characterize the antioxidants present in the bitter tea brewed from the leaves of LP. It was found that the crude glycoside fraction possessed strong protection against oxidation of human low-density lipoprotein (LDL). The column chromatographic separation led to the isolatation of five phenylethanoid glycosides, namely, acteoside, Ligupurpuroside A, cis-ligupurpuroside B, trans-ligupurpuroside B, and osmanthuside B. When acteoside was heated in the boiling water, it was isomerized to form isoacteoside. Acteoside, isoacteoside, and Ligupurpuroside A purified from LP were protective, whereas cis-ligupurpuroside B, trans-ligupurpuroside B, and osmanthuside B exhibited no protection to human LDL from Cu(2+)-medicated oxidation. Acteoside, isoacteoside, and Ligupurpuroside A were also effective in preventing the peroxyl free radical-induced oxidation of alpha-tocopherol in human LDL. The antioxidant activities of acteoside, isoacteoside, and Ligupurpuroside A were comparable to that observed for a green tea antioxidant, (-)-epicatechin gallate. The inhibitory effect of these three phenylethanoid glycosides on oxidation of human LDL and alpha-tocopherol was dose-dependent at concentrations of 5-40 μM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ligupurpuroside A

Compound Identifiers

PubChem CID

85143827