Isovanillin

SKU: orb1221577

Description

Isovanillin is an aldehyde oxidase inhibitor. Antispasmodic activities. Antidiarrheal activities.

Key Properties

• CAS Number: 621-59-0
• MW: 152.15
• Purity: >98% (HPLC)
• Formula: C₈H₈O₃
• SMILES: COC1=C(C=C(C=C1)C=O)O
• Target: Others
• Solubility: In Vitro: DMSO : 100 mg/mL (657.25 mM)

Bioactivity

• In Vivo:
  Isovanillin (2 mg/kg & 5 mg/kg) and iso-acetovanillon (2 mg/kg & 5 mg/kg) both have antidiarrheal and anti-motility effect on gastrointestinal tract.
• In Vitro:
  Isovanillin is not a substrate for aldehyde oxidase and therefore it is metabolized to isovanillic acid predominantly by aldehyde dehydrogenase. Isovanillin is relaxant of ileum contractions induced by 5-HT (IC50 = 356±50 μM).
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Others