Ipratropium bromide monohydrate

SKU: orb1310939

Description

Ipratropium bromide monohydrate is a hydrated salt form of the muscarinic antagonist ipratropium, structurally analogous to atropine. It is widely utilized in respiratory research for investigating bronchospasm and rhinitis mechanisms in vitro and in vivo, owing to its localized action and favorable safety profile for inhalation.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 66985-17-9
• MW: 430.38
• Purity: 99.37% (May vary between batches)
• Formula: C₂₀H₃₂BrNO₄
• SMILES: O.[Br-].CC(C)[N+]1(C)[C@H]2CC[C@H]1CC(C2)OC(=O)C(CO)c1ccccc1
• Target: AChR
• Solubility: Ethanol:200 mM;DMSO:55 mg/mL (127.79 mM)

Bioactivity

• Target IC50:
  M2 mAChR:2 nM|M1 mAChR:2.9 nM|M3 mAChR:1.7 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Ipratropium bromide, Ipratropium Bromide, Ipratropium bromide hydrate, Ipratropium bromide Hydrate, Ipratropium bromide Monohydrate, Ipratropium bromide monohydrate, Muscarinic acetylcholine receptor, ischaemia/reperfusion, mAChR, Inhibitor, I/R, asthma, chronic obstructive pulmonary disease, Sch 1000 bromide

Compound Identifiers

PubChem CID

168008614