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IBT6A

SKU: orb1220001

Description

IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.

Images & Validation

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Key Properties

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CAS Number1022150-12-4
MW386.45
Purity>98% (HPLC)
FormulaC22H22N6O
SMILESNc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCNC1
TargetBTK
SolubilityIn Vitro: DMSO : 50 mg/mL (129.38 mM)

Bioactivity

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In Vitro
IBT6A (Compound 14) can be used in synthesis of Ibrutinib and Ibrutinib-based activity-based probes (ABPs).

Storage & Handling

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StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information