Gal-ARV-771

SKU: orb3134090

Description

Gal-ARV-771 is a PROTAC prodrug, modified with galactose, based on ARV-771. It is activated in senescent cancer cells that express SA-β-Gal, thereby releasing ARV-771. Through the ubiquitin-proteasome pathway, Gal-ARV-771 induces selective degradation of the BRD4 protein in senescent cells and promotes apoptosis (apoptosis) of these cancer cells.

Research Area

Cell Biology, Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

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Key Properties

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Formula	C₇₁H₈₄ClN₉O₁₉S₂
Target	Apoptosis,Epigenetic Reader Domain,PROTACs

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Apoptosis,Epigenetic Reader Domain,PROTACs

Protocol Information

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Gal-ARV-771

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