GABAA receptor agent 2 TFA

SKU: orb1687618

Description

GABAA receptor agent 2 TFA is a potent and selective GABAA receptor antagonist, exhibiting high affinity with an IC50 of 24 nM at human α1β2γ2 receptors and a Ki of 28 nM at rat receptors. It shows no activity against human GABA transporters (hGAT-1, hBGT-1, hGAT-2, hGAT-3), making it a useful tool for studying GABAergic neurotransmission in neuropharmacology and electrophysiology research.

Research Area

Neuroscience, Neuroscience; Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1781880-44-1
• MW: 433.42
• Formula: C₂₂H₂₂F₃N₃O₃
• SMILES: O=C(O)C(F)(F)F.ON1N=CC(=C1C=2C=CC=C(C2)C=3C=CC=CC3)C4CCNCC4
• Target: GABA Receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90488945