Fusidic acid sodium salt

SKU: orb1309108

Description

Fusidic acid sodium salt is the sodium salt form of a bacteriostatic antibiotic originally isolated from Fusidium coccineum. It is widely used in topical formulations for skin infections and serves as a key research tool for studying bacterial protein synthesis and antibiotic resistance mechanisms in both in vitro and in vivo models.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 751-94-0
• MW: 538.69
• Purity: 99.84% (May vary between batches)
• Formula: C₃₁H₄₇NaO₆
• SMILES: [C@]12([C@@]3([C@H](/C(=C(\CCC=C(C)C)/C(=O)[O-])/[C@H](C3)OC(=O)C)C[C@H]([C@H]1[C@@]1([C@@H](CC2)[C@@H]([C@@H](CC1)O)C)C)O)C)C.[Na+]
• Target: Interleukin,Antibacterial,Antibiotic
• Solubility: H2O:92 mg/mL (170.78 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.13 mM);Ethanol:93 mg/mL (172.64 mM);DMSO:93 mg/mL (172.64 mM)

Bioactivity

• In Vivo:
  Fusidin(Fusidate Sodium) ameliorates EAM, at least partly, through an inhibitory action on the secretion of TNF-a. It markedly attenuates clinical and histological signs of immunoinflammatory diabetes mellitus in mice given streptozotocin(SZ). The effect is dose-dependent, observed in three different strains of mice. Thus, fusidin might have an antidiabetogenic effect.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CAT, bacteriostatic, Bacterial, Antibiotic, Fusidic acid sodium salt, Fusidic acid sodium, Fusidate Sodium, Fusidic acid, growth, elongation factor G (EF-G), elongation, factor, Fucidin, Inhibitor, inhibit, SQ 16360, SQ16360, SQ-16360, Sodium fusidate, steroids, ribosome

Compound Identifiers

PubChem CID

23672955