FPH1

SKU: orb1300708

Description

FPH1 (BRD-6125) is a small molecule that facilitates the proliferation of hepatocytes derived from induced pluripotent stem cells (iPSCs). It is a valuable research tool for liver disease modeling, drug toxicity screening, and studying hepatic development and regeneration in vitro.

Research Area

Metabolism Research

Key Properties

• CAS Number: 708219-39-0
• MW: 388.817
• Purity: 99.91% (May vary between batches)
• Formula: C₁₆H₁₅ClF₂N₂O₃S
• SMILES: CC1=C(C=C(Cl)C=C1)N(CC(=O)NC1=C(F)C=CC=C1F)S(C)(=O)=O
• Target: Others,Cytochromes P450
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:72 mg/mL (185.18 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.49 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vitro:
  FPH1 induces functional proliferation of hepatocytes in vitro, and causes more pronounced hepatocyte morphologies, including polygonal cell shapes, visible nuclei, and more noticeable bile cannaliculi between hepatocytes.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FPH 1, FPH1, FPH-1, Inhibitor, inhibit, BRD-6125, BRD6125, BRD 6125

Compound Identifiers

PubChem CID

2210370