Fluocinolone (Acetonide)

SKU: orb1310684

Description

Fluocinolone acetonide is a synthetic glucocorticoid used in topical formulations to treat dermatological conditions. It is also applied in ophthalmic, otic, and nasal inflammation research, serving as a tool for studying anti-inflammatory and immunosuppressive mechanisms in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 67-73-2
• MW: 452.4882
• Purity: 99.82% (May vary between batches)
• Formula: C₂₄H₃₀F₂O₆
• SMILES: CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO
• Target: Glucocorticoid Receptor,Wnt/beta-catenin
• Solubility: DMSO:83 mg/mL (183.43 mM);Ethanol:10 mg/mL (22.1 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.29 mM)

Bioactivity

• Target IC50:
  GR:2.0 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Glucocorticoid Receptor, GlucocorticoidReceptor, Flucort-N, Fluocinolone, Fluocinolone (Acetonide), Fluocinolone acetonide, Inhibitor, inhibit, Acetonide

Compound Identifiers

PubChem CID

6215