(E)-Ethyl p-methoxycinnamate

SKU: orb1304666

Description

(E)-Ethyl p-methoxycinnamate (EPMC) is a bioactive small molecule functioning as a glutathione S-transferase inhibitor with reported anticarcinogenic properties. It is utilized in biochemical research to study chemoprevention and detoxification pathways in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 24393-56-4
• MW: 206.24
• Purity: 97.56% (May vary between batches)
• Formula: C₁₂H₁₄O₃
• SMILES: CCOC(=O)\C=C\C1=CC=C(OC)C=C1
• Target: Mitochondrial Metabolism,Caspase,Apoptosis,COX,glycosidase
• Solubility: DMSO:37 mg/mL (179.4 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.7 mM)

Bioactivity

• Target IC50:
  COX-1:1.12 μM (IC50)|COX-2:0.83 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclooxygenase, COX, 4-Methoxycinnamic Acid Ethyl Ester, (E)Ethyl pmethoxycinnamate, (E) Ethyl p methoxycinnamate, Inhibitor, Ethyl p-methoxycinnamate, EPMC, Ethyl methoxycinnamate, Ethyl para-methoxycinnamate, Ethyl 4-methoxycinnamate, inhibit

Compound Identifiers

PubChem CID

5281783