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DprE1-IN-1

SKU: orb1223281

Description

TBA-7371 is a non-covalent inhibitor of decaprenylphosphoryl-β-D-ribose 2’-epimerase (DprE1) with an IC50 value of 10 nM. It also inhibits PDE6 with an IC50 value of 4 μM.1 AZ 7371 has been shown to be active against M. tuberculosis with an MIC range of 0.78-3.12 μM and demonstrates efficacy in a rodent model of tuberculosis.

Images & Validation

Key Properties

CAS Number1494675-86-3
MW355.39
Purity>98% (HPLC)
FormulaC18H21N5O3
SMILESCc1cc2c(c(cn2Cc2c(c(ncn2)OC)C)C(=O)NCCO)nc1
TargetCDK
SolubilityDMSO : 11 mg/mL. 30.95 mM;

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TBA-7371 | TBA 7371 | TBA7371

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Protocol Information

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$ 60.00
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100 mg
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