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DAM-001

SKU: orb3174102

Description

DAM-001 (Z236004662) is a potent non-competitive allosteric inhibitor of the human dopamine transporter (hDAT). It exhibits an IC50 of 24.70 μM in the absence of the orthosteric inhibitor Nomifensine and 1.026 μM when Nomifensine is present.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1090396-31-8
MW297.4
FormulaC18H23N3O
SMILESO=C(N1CCCC(C2=NC=3C=CC=CC3N2)C1)C4CCCC4
TargetDopamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information