Creatinine

SKU: orb1310556

Description

Creatinine (NSC-13123) is a metabolic waste product derived from muscle creatine, routinely measured in serum as a key biomarker for assessing renal function. It is widely utilized in both in vitro assays and in vivo studies to model kidney disease and evaluate nephrotoxicity in preclinical research.

Research Area

Kidney & Urological Research, Metabolism Research

Key Properties

• CAS Number: 60-27-5
• MW: 113.12
• Purity: 99.36% (May vary between batches)
• Formula: C₄H₇N₃O
• SMILES: NC=1N(C)CC(=O)N1
• Target: Endogenous Metabolite
• Solubility: H2O:50 mg/mL (442.01 mM);DMSO:1.18 mg/mL (10.43 mM)

Bioactivity

• In Vitro:
  Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EndogenousMetabolite, Endogenous Metabolite, Creatinine, NSC13123, NSC-13123, NSC 13123, Inhibitor, inhibit

Compound Identifiers

PubChem CID

588