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Cobiprostone

SKU: orb3174269

Description

Cobiprostone (SPI 8811) is an activator of type 2 chloride channels. This compound prevents depolarization of the mitochondrial membrane potential caused by Indomethacin and reverses the loss of mitochondrial membrane potential. Cobiprostone offers cellular protection against damage induced by non-steroidal anti-inflammatory drugs.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number333963-42-1
MW404.5
FormulaC21H34F2O5
SMILESC(CCCCCC(O)=O)[C@@H]1[C@@]2([C@](O[C@]([C@](C[C@H](CC)C)(F)F)(O)CC2)(CC1=O)[H])[H]
TargetChloride channel,Mitochondrial Metabolism

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information