Cimetidine

SKU: orb1310283

Description

Cimetidine is a histamine H2 receptor antagonist that competitively inhibits histamine binding, leading to suppressed gastric acid, pepsin, and gastrin secretion. It is widely used in research involving gastrointestinal physiology, ulcer models, and receptor studies in both in vitro and in vivo experimental settings.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 51481-61-9
• MW: 252.339
• Purity: 99.82% (May vary between batches)
• Formula: C₁₀H₁₆N₆S
• SMILES: CNC(NCCSCC1=C(C)NC=N1)=NC#N
• Target: Antibacterial,Histamine Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:3 mg/mL (11.89 mM);DMSO:245 mg/mL (970.91 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (9.91 mM)

Bioactivity

• Target IC50:
  Histamine receptor:0.6 μM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SKF 92334, SKF92334, SKF-92334, inverse, Inhibitor, inhibit, HistamineReceptor, Histamine Receptor, H2 receptor, Cimetidine, anti-cancer, anti-inflammatory

Compound Identifiers

PubChem CID

2756