cIAP1 ligand 1

SKU: orb1909227

Description

cIAP1 ligand 1 is a proteolysis-targeting chimera (PROTAC) based on an LCL161 derivative that recruits E3 ubiquitin ligases to induce target protein degradation. It is used in prostate cancer research, particularly in conjunction with androgen receptor ligands, for developing novel degraders and has been applied in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2095244-42-9
• MW: 598.75
• Purity: 98.77% (May vary between batches)
• Formula: C₃₁H₄₂N₄O₆S
• SMILES: C[C@H](N(C)C(=O)OC(C)(C)C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1cccc(O)c1
• Target: Others,Ligands for E3 Ligase
• Solubility: DMSO:80 mg/mL (133.61 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cIAP1, cIAP1 ligand 1, cIAP-1 ligand 1, E3 ligase Ligand 12

Compound Identifiers

PubChem CID

138911355