Chrysosplenetin

SKU: orb1297672

Description

Chrysosplenetin is a natural flavonoid known to inhibit the metabolism of artemisinin. This compound is used in pharmacological research to study drug-drug interactions and resistance mechanisms in malaria, employing both in vitro enzyme assays and in vivo parasite models.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 603-56-5
• MW: 374.34
• Purity: 98.53% (May vary between batches)
• Formula: C₁₉H₁₈O₈
• SMILES: COc1cc(ccc1O)-c1oc2cc(OC)c(OC)c(O)c2c(=O)c1OC
• Target: P-gp,Ferroptosis,Cytochromes P450
• Solubility: DMSO:50 mg/mL (133.57 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.34 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ABCB1, CYPs, Cytochrome P450, Cluster of differentiation 243, Chrysosplenetin, Chrysosptertin B, CD243, Inhibitor, MDR1, Ferroptosis, inhibit, Multidrug resistance protein 1, Pgp, P-gp, P-gp (P-glycoprotein), P-glycoprotein

Compound Identifiers

PubChem CID

5281608