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Chlorzoxazone

SKU: orb1307897

Description

Chlorzoxazone is a centrally acting skeletal muscle relaxant used in research to study spasticity and pain models. Its application extends to in vitro investigations of cytochrome P450 2E1 (CYP2E1) activity and in vivo experiments for evaluating myorelaxant effects.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number95-25-0
MW169.565
Purity99.72% (May vary between batches)
FormulaC7H4ClNO2
SMILESClC1=CC=C2OC(=O)NC2=C1
TargetBeta Amyloid,Potassium Channel,FOXO,Cytochromes P450
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.79 mM);Ethanol:32 mg/mL (188.71 mM);DMSO:45 mg/mL (265.38 mM)

Bioactivity

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In Vivo
Chlorzoxazone is a central acting skeletal muscle relaxant that operates by suppressing reflex actions in the spinal column. It is capable of activating rat brain SK2 channel currents within cells. Metabolically, Chlorzoxazone is primarily transformed by CYP2E1 into 6-hydroxychlorzoxazone. Other human liver cytochrome P450 enzymes, such as CYP1A1, CYP1A2, and CYP3A4, may also contribute to its metabolism.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Chlorzoxazon, Chlorzoxazone, Cytochrome P450, CYPs, inhibit, Inhibitor, Paraflex, Potassium Channel, PotassiumChannel

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

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No computed properties available.

Protocol Information

Available Sizes

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1 g
$ 70.00
5 g
$ 90.00
10 g
$ 110.00
DispatchUsually dispatched within 5-10 working days
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