Chlorhexidine dihydrochloride

SKU: orb1309608

Description

Chlorhexidine dihydrochloride

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3697-42-5
• MW: 578.38
• Purity: 99.39% (May vary between batches)
• Formula: C₂₂H₃₂Cl₄N₁₀
• SMILES: c1(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(cc2)Cl)ccc(cc1)Cl.Cl.Cl
• Target: Necroptosis,Antifection,Antibiotic,Apoptosis,Cell wall,Antibacterial
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.71 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:93 mg/mL (160.79 mM)

Bioactivity

• In Vitro:
  Chlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cell wall, cell wall, Cellwall, Chlorhexidine 2HCl, Chlorhexidine, Chlorhexidine hydrochloride, Chlorhexidine dihydrochloride, Chlorhexidine Dihydrochloride, Chlorhexidine Hydrochloride, Bacterial, Antibiotic, CAT, Inhibitor, HNMT, inhibit, NSC 185, NSC185, NSC-185

Compound Identifiers

PubChem CID

62517