Cefoselis Sulfate

SKU: orb1223382

Description

Cefoselis sulfate is a stable cephalosporin for BETA-lactamase. The drug shows antimicrobial activity for a wide range of bacteria including Pseudomonas.(In Vitro):The activity of Cefoselis (sulfate) was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis sulfate showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis. Cefoselis sulfate was highly active against MSSA and MSCNS. Cefoselis sulfate was poor in the activity against MRSA, MRCNS,PRSP and Enterococcus faecalis,and no activity for Enterococcus faecium.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 122841-12-7
• MW: 620.64
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₂N₈O₆S₂·H₂SO₄
• SMILES: CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CN4C=CC(=N)N4CCO)C(=O)O.OS(=O)(=O)O
• Target: CXCR
• Solubility: DMSO : ≥ 6.4 mg/mL. 10.31 mM

Bioactivity

• In Vitro:
  The activity of Cefoselis (sulfate) was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis sulfate showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis. Cefoselis sulfate was highly active against MSSA and MSCNS. Cefoselis sulfate was poor in the activity against MRSA, MRCNS, PRSP and Enterococcus faecalis, and no activity for Enterococcus faecium.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Winsef

Quick Database Links

Gene Symbol

CXCR