Bruceine E

SKU: orb1297540

Description

Bruceine E is a natural compound isolated from Brucea javanica seeds, studied for its hypoglycemic properties. It functions as an insulin secretagogue, making it a useful research tool for investigating diabetes mechanisms in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 21586-90-3
• MW: 412.43
• Purity: 99.88% (May vary between batches)
• Formula: C₂₀H₂₈O₉
• SMILES: O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=C[C@H](O)[C@H]5O)[H])([C@@H](O)[C@H](O)[C@@]2(C)OC4)[H]
• Target: Others
• Solubility: DMSO:50 mg/mL (121.23 mM)

Bioactivity

• In Vivo:
  Bruceine E (1 mg/kg b.w.) exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose.
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• In Vitro:
  Bruceine E exhibits significant blood glucose concentration reduction activity.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antidiabetic, Bruceine E, inhibit, Inhibitor, hypoglycemia, effect, quassinoid

Compound Identifiers

PubChem CID

5315510