Bromperidol

SKU: orb1219157

Description

Bromperidol is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia. (In Vivo):Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats.Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 10457-90-6
• MW: 420.32
• Purity: >98% (HPLC)
• Formula: C₂₁H₂₃BrFNO₂
• SMILES: OC1(CCN(CCCC(c(cc2)ccc2F)=O)CC1)c(cc1)ccc1Br
• Target: 5-HT Receptor
• Solubility: DMSO:50 mg/mL (118.96 mM; Need ultrasonic)

Bioactivity

• In Vivo:
  Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats. Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

R-11333

Quick Database Links

Gene Symbol

5-HT Receptor