Bazedoxifene acetate

SKU: orb1305337

Description

Bazedoxifene acetate is a selective estrogen receptor modulator (SERM) developed for research. It is utilized in preclinical studies to investigate bone metabolism and breast tissue, with applications in both in vitro receptor binding assays and in vivo models of osteoporosis.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 198481-33-3
• MW: 530.67
• Purity: >99.99% (May vary between batches)
• Formula: C₃₂H₃₈N₂O₅
• SMILES: C(=O)(C)O.c1c(cc2c(c1)n(c(c2C)c1ccc(cc1)O)Cc1ccc(cc1)OCCN1CCCCCC1)O
• Target: Estrogen Receptor/ERR,Estrogen/progestogen Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.54 mM);DMSO:137 mg/mL (258.16 mM)

Bioactivity

• Target IC50:
  ERβ:99 nM|ERα:26nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bazedoxifene, Bazedoxifene acetate, Bazedoxifene Acetate, inhibit, modulator, Inhibitor, interactions, IL-6/GP130, ERR, ERβ, ERα, estrogen, Estrogen Receptor/ERR, EstrogenReceptor, Estrogen Receptor, STAT3, TSE424, TSE-424, TSE 424, protein-protein, progestogenReceptor, progestogen Receptor, receptor, WAY-TES 424, WAY-TES424, WAY-TES-424, WAY140424, WAY-140424, selective, SERM, WAY 140424

Compound Identifiers

PubChem CID

154256