AZD9362

SKU: orb3173835

Description

AZD9362 is a reversible, ATP-competitive inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) and the insulin receptor (insulin receptor) with oral bioavailability. It inhibits IGF-1R enzyme activity with an IC50 value of 14 nM. AZD9362 enhances the antitumor effects of AZD5363 and can be applied in cancer research, including studies on breast cancer.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1905412-80-7
• MW: 494.98
• Formula: C₂₄H₂₇ClN₈O₂
• SMILES: ClC=1C(C2=C3N(N=C2)C=CC=C3)=NC(NC4=C(C)N(N=C4C)C5CCN(C([C@@H](C)O)=O)CC5)=NC1
• Target: IGF-1R

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IGF-1R