AVS Bio - Human NY-ESO (CTAG1B) monoclonal antibody (clone 912G4 )

SKU: PODI-0093

Description

Antibody against NY-ESO (New York Esophageal Squamous Cell Carcinoma 1). NY-ESO is a cancer-testis antigen encoded by the CTAG1B gene and is normally expressed only in germ cells of the testis but aberrantly expressed in various cancers, including melanoma, lung, ovarian, and esophageal carcinomas. It is one of the most immunogenic tumor antigens known, capable of eliciting both humoral and cellular immune responses. Because of its restricted normal expression and high tumor specificity, NY-ESO is a prominent target for cancer immunotherapy, vaccine development, and tumor biomarker studies.

Research Area

Cancer Biology

Images & Validation

• Tested Applications: ELISA
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: 9B12G4
• Immunogen: Purified recombinant full-length NY-ESO expressed in HEK293 cells
• Target: Human NY-ESO, ECD
• Purification: affinity purified, >95%
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS
• Concentration: 0.5 mg/ml
• Expiration Date: For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Human NY-ESO, ECD