AVS Bio - Human polo kinase 1 (PLK1) mouse monoclonal antibody (clone 2F2F2)

SKU: PODI-0019

Description

Antibody against human polo kinase 1 (PLK1). PLK1 is a serine/threonine kinase that plays a pivotal role in regulating multiple stages of mitosis, including centrosome maturation, spindle assembly, chromosome segregation, and cytokinesis. Its activity is tightly controlled during the cell cycle, peaking during G2/M phase. Overexpression of PLK1 is frequently observed in various cancers and is associated with poor prognosis, making it an important target for anticancer therapy. Antibodies against PLK1 are used in studies of cell division, checkpoint control, and cancer progression.

Research Area

Cancer Biology

Images & Validation

• Tested Applications: WB
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1, Kappa
• Clone No.: 2F2F2
• Immunogen: Human polo kinase 1, kinase domain (amino acids 15-361)
• Target: Human Polokinase 1 kinase domain 15-361 (PLK1)
• Purification: affinity purified, >95%
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS
• Concentration: 0.5 mg/ml
• Expiration Date: For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Human Polokinase 1 kinase domain 15-361 (PLK1)