AVS Bio - mouse human PKM2 Antibody

SKU: PODI-0081

Description

Antibody against pyruvate kinase isoenzyme type M2 (PKM2 or M2-PK), one of the two isozymes encoded by the human PKM gene. The two isozymes M1 and M2 are alternative splicing products and differ in one of eleven exons. Pyruvate kinase is a critical enzyme in glycolysis as it dephosphorylates phosphoenolpyruvate (PEP) to pyruvate resulting in the net production ATP. PKM2 is mainly found in differentiated tissues such as lung as well as in rapidly proliferating cells including tumor cells.

Research Area

Cancer Biology

Images & Validation

• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: ES2
• Target: Human pyruvate kinase isoform M2 (PKM2), no cross reaction with L, R, M1
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: solution
• Expiration Date: For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Human pyruvate kinase isoform M2 (PKM2), no cross reaction with L, R, M1