AVS Bio - mouse anti-human BCHE

SKU: PODI-0071

Description

Antibody against butyrylcholinesterase (BChE), also known as pseudocholinesterase, is a disulfide linked tetrameric enzyme produced by the liver and also found in the blood circulation. Its function is not fully understood but it is known to hydrolyze a range of (choline) esters and therefore important for the detoxification of drugs and toxins including the muscle relaxant succinylcholine and several pesticides. In the healthy brain, cholinesterase is mainly responsible for regulating acetyl choline levels while BChE plays a minor role. In contrast, BChE activity is reported to be increased in Alzheimer’s disease patients and it was suggested that selective inhibition of BChE could have a therapeutic effect.

Images & Validation

• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone No.: 14
• Target: Human butyrylcholinesterase (BCHE)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: solution
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Human butyrylcholinesterase (BCHE)