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Apicidin D2

SKU: orb3173487

Description

Apicidin D2 (Compound 4) is a fungal metabolite that functions as an AgrA quorum sensing inhibitor. It exhibits antivirulence activity by non-bactericidally inhibiting the activation of methicillin-resistant Staphylococcus aureus (MRSA) Agr, demonstrating potent inhibitory effects on all Agr types. Apicidin D2 is useful for researching MRSA infections.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number177562-78-6
MW625.81
FormulaC34H51N5O6
SMILESC(C=1C=2C(N(OC)C1)=CC=CC2)[C@H]3C(=O)N[C@@]([C@H](CC)C)(C(=O)N4[C@@](C(=O)N[C@@H](CCCCC[C@H](CC)O)C(=O)N3)(CCCC4)[H])[H]
TargetAntibacterial,Endogenous Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information