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Antazoline

SKU: orb1310946

Description

Antazoline hydrochloride

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number2508-72-7
MW301.8
Purity99.76% (May vary between batches)
FormulaC17H20ClN3
SMILESCl.C(N(CC1=CC=CC=C1)C1=CC=CC=C1)C1=NCCN1
TargetGPCR
Solubility10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.63 mM);DMSO:45 mg/mL (149.1 mM);Ethanol:4 mg/mL (13.25 mM);H2O:14 mg/mL (46.39 mM)

Bioactivity

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In Vivo
At a concentration of 30 μM, Antazoline effectively reduces neurotoxicity mediated by NMDA and also blocks NMDA-induced currents via a voltage-dependent and rapidly reversible action, with an inhibition rate of 85±3% at a voltage of -60 mV.
In Vitro
In the model of sustained epileptic state induced by picrotoxin, Antazoline can be utilized to protect the intrinsic neural circuitry.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Antazoline, Antazoline HCl, Antazoline hydrochloride, Antazoline Hydrochloride, inhibit, Inhibitor, H1 receptor, HistamineReceptor, Histamine Receptor, Phenazocine HCl, Phenazoline, Phenazoline Hydrochloride, Phenazoline hydrochloride

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Quality Guarantee

Quality Guarantee

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Key Properties

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No computed properties available.

Protocol Information

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
1 g
$ 70.00
DispatchUsually dispatched within 5-10 working days
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