Amoxicillin trihydrate

SKU: orb1224460

Description

Amoxicillin Trihydrate is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.(In Vitro):Amoxicillin (Amoxycillin) trihydrate (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.(In Vivo):Amoxicillin (Amoxycillin) trihydrate (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.Amoxicillin (Amoxycillin) trihydrate (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 61336-70-7
• MW: 419.45
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₉N₃O₅S·3H₂O
• SMILES: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N)C3=CC=C(O)C=C3)=O)N1C2=O)O.[H]O[H].[H]O[H].[H]O[H]
• Target: Antibacterial
• Solubility: soluble in Water

Bioactivity

• In Vivo:
  Amoxicillin (Amoxycillin) trihydrate (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less. Amoxicillin (Amoxycillin) trihydrate (1.6-9.5 mg/kg; p.o. ; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice. Animal model: Female ICR/Swiss mice. Dosage: 7 mg/kg. Administration: Subcutaneous injection; every 8 h, for 24 hours. Result: Inhibited bacterial numbers in a dose-dependent manner. Animal model: Female ICR/Swiss mice. Dosage: 7 mg/kg. Administration: Subcutaneous injection; every 8 h, for 4 days. Result: Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality. Animal model: Swiss albino mice. Dosage: 1.6 and 9.5 mg/kg. Administration: Oral administration; daily, for 7 or 14 days. Result: Improved the activity of Chlamydia trachomatis infection in mice.
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• In Vitro:
  Amoxicillin (Amoxycillin) trihydrate (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner. They are for reference only. Amoxicillin trihydrate 相关抗体:
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Amoxicillin Trihydrate | Amoxicillin 3H2O | Larotid | Amoxil | Amoxipen | Moxaline

Quick Database Links

Gene Symbol

Antibacterial