Amoxicillin

SKU: orb1225468

Description

Amoxicillin is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.(In Vitro):Amoxicillin (Amoxycillin) (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.(In Vivo):Amoxicillin (Amoxycillin) (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.Amoxicillin (Amoxycillin) (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 26787-78-0
• MW: 365.4
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₉N₃O₅S
• SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C
• Target: Others
• Solubility: DMSO: 73 mg/mL (199.78 mM)

Bioactivity

• In Vivo:
  Animal model: Female ICR/Swiss mice. Dosage: 7 mg/kg. Administration: Subcutaneous injection; every 8 h, for 24 hours. Result: Inhibited bacterial numbers in a dose-dependent manner. Animal model: Female ICR/Swiss mice. Dosage: 7 mg/kg. Administration: Subcutaneous injection; every 8 h, for 4 days. Result: Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality. Animal model: Swiss albino mice. Dosage: 1.6 and 9.5 mg/kg. Administration: Oral administration; daily, for 7 or 14 days. Result: Improved the activity of Chlamydia trachomatis infection in mice.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Amoxycillin | Amoxicilline | Amoxicillin anhydrous | Clamoxyl

Quick Database Links

Gene Symbol

Others